Differences

This shows you the differences between two versions of the page.

--- ms [2025/09/07 04:54] – miko
+++ ms [2025/11/25 16:37] (current) – external edit 127.0.0.1
@@ Line 25: / Line 25: @@
 ===== Conclusion =====
 While there is currently no cure for MS, early diagnosis and treatment can help manage symptoms, reduce relapses, and improve quality of life. Advances in medicine and therapy continue to offer hope and support for those living with this complex condition
+====== Ocrevus (ocrelizumab) – Medication Overview ======
+Ocrevus is a prescription medicine used to treat certain forms of multiple sclerosis (MS). It is a humanized monoclonal antibody that targets CD20-positive B cells, which are believed to play a role in the disease process.
+===== 🧬 Mechanism of Action =====
+Ocrevus binds to the CD20 protein found on the surface of B cells. By depleting these cells, it helps reduce inflammation and slow the progression of MS.
+===== 🎯 Approved Indications =====
+  * **Relapsing-remitting MS (RRMS)** – Reduces the frequency of relapses and MRI activity.
+  * **Primary progressive MS (PPMS)** – Slows disability progression; first approved treatment for this form.
+===== 💉 Administration =====
+  * Given as an **intravenous infusion** every 6 months.
+  * The first dose is split into two infusions (Day 1 and Day 15).
+  * Subsequent doses are single infusions every 24 weeks.
+===== ⚠️ Common Side Effects =====
+  * Infusion-related reactions (fever, rash, throat irritation)
+  * Increased risk of infections (e.g. respiratory, herpes)
+  * Possible reduction in immunoglobulin levels over time
+===== 📋 Monitoring and Safety =====
+  * **Hepatitis B screening** required before starting treatment.
+  * **Vaccinations** should be updated prior to therapy; live vaccines are not recommended during treatment.
+  * Regular **blood tests** and clinical monitoring are advised.
+===== 🧾 Additional Notes =====
+  * Not recommended during pregnancy or breastfeeding.
+  * Effective contraception is advised during treatment and for 6 months after the last dose.
+  * Patients should remain under the care of a neurologist or MS specialist.
+===== 🔗 References =====
+This summary is based on publicly available medical guidelines and product information. Always consult your healthcare provider for personalized advice.